The immune system relies on antibodies that can recognize only a single protein. “We wanted to figure out methods to graft complete, intact electronic circuits onto colloidal particles”, explains Michael Strano, the Carbon C. Dubbs Professor of Chemical Engineering at MIT and senior author of the study, which was published today in the journal Nature Nanotechnology. This can be a very powerful framework for looking at many kinds of (biological) systems. We gather the latest popular science, engineering centers and more.
Trends in the university of California’s patent portfolio are “Nucleic Acid” , “Microfluidic Device” , “Plant” , “Synthetic” , “DNA”. If we look at the heart, such as, it emits electromagnetic fields which change according to our emotions, and these can actually be measured up to several feet away from the human body. Manish Butte and colleagues in engineering have developed a new way to use atomic force microscopy to rapidly map cells by making a major advancement in a technology invented at Stanford in 1986.
Postdoctoral scholar Haifeng Wang, PhD, is the lead author. A new technique introduced by a collaboration of researchers used a proteomics approach developed by researchers at Oak Ridge National Laboratory, in Tennessee, to find who ate what. Other “artificial” mutations induced by the researchers, that do not correspond to any known naturally occurring mutations, can be used to better understand the function of the specific part of the gene affected by that mutation. The research was funded by the National Science Foundation (NSF), Air Force Office of Scientific Research (AFOSR), and U. S. Department of Energy. To view proteins by both microscopes and correlate them, the researchers developed a method of tagging the proteins. To enable them to view this process, Dr. Blanchard’s team developed new reporter molecules called fluorophores that emit fluorescent light and can be attached to the GPCR to tell on its motions when adrenaline binds. A recent study that describes how researchers have used ribosome profiling to find several hundred long non-coding RNAs can give rise to small peptides. The method allows direct quantification of the messenger RNA fragments protected by the ribosome after digestion with the enzyme nuclease.
The researchers were able to visualize translation and the movement of the ribosome every three nucleotides, which corresponds to the size of each codon on the RNA producing an Amino Acid. Earlier work showed that a long non-coding RNA produced by the tarsal-less polished rice mille-pattes gene encodes small peptides that control epithelial morphogenesis in Drosophila and the flour beetle Tribolium.
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Now, scientists from the university of Chicago have devised a novel method for creating high-quality, specific and reproducible antibodies that drop an “antibody bottleneck” that has plagued genomics research. For example, the researchers found that during development, when olfactory neurons are choosing connection partners, the gene expression patterns from different neuronal types are different. Researchers say that what makes this new nano-scale thin-film material with the highest conductivity in its class. “The high conductivity and wide bandgap make this an ideal material for making optically transparent conducting films which could be used in a variety of electronic devices, including high power electronics, electronic displays, touchscreens and even solar cells in which light needs to pass through the device”, said Bharat Jalan, a University of Minnesota chemical engineering and materials science professor and the lead researcher on the study.